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Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules
accompanied by re-expression of tumour suppressors connected to increased patient survival
CAS Number: 548-90-3
CAS Number: 99-76-3
VERU-111 inin (HA) Peptide Structural Insights into the PharmacophoreVERU 111 (ABI 231) is a potent and orally active and tubulin inhibitor, which displays strong antiproliferative activity, with an average IC50 of 5. 2 nM against panels of melanoma and prostate cancer cell lines. VERU 111 (ABI 231) suppresses tumor growth and metastatic phenotypes of cervical cancer cells via targeting HPV E6 and E7, and has potential for the treatment of prostate cancer. Product information CAS Number: 1332881 26 1 Molecular Weight: