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Dual PARP EGFR ligand for PROTAC Catalog No.:M17144-C Chemical Name: (2E)-N-(2-aminophenyl)-3-{1-[4-(1-methyl-1H-pyrazol-4-yl)benzenesulfonyl]-1H-pyrrol-3-yl}prop-2-enamide

SKU: 70165967152

4.3
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Description

Chemical Name: (2E)-N-(2-aminophenyl)-3-{1-[4-(1-methyl-1H-pyrazol-4-yl)benzenesulfonyl]-1H-pyrrol-3-yl}prop-2-enamide

Navelbine base

Smiles: C[C@]12C[C@]3(C[C@H]1CCC[C@@H]2C)C(=C)COC3=O

InChi: InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6

Dual PARP EGFR ligand for PROTAC Catalog No.:M17144-C Chemical Name: (2E)-N-(2-aminophenyl)-3-{1-[4-(1-methyl-1H-pyrazol-4-yl)benzenesulfonyl]-1H-pyrrol-3-yl}prop-2-enamideDual PARP EGFR ligand for PROTAC incorporates a ligand for PARP and EGFR , and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). Dual PARP EGFR ligand for PROTAC can be used in the synthesis of DP C 4, which is CRBN based dual PROTAC for simultaneous degradation of EGFR and PARP. Product information Molecular Weight: 1020. 52 Formula: C53H56ClF2N9O8 Chemical Name: 6 ((4 ((3 chloro 4 fluorophenyl)amino) 7 methoxyquinazolin 6

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