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RG7834 is a novel oral HBV viral gene expression inhibitor that blocks viral antigen and virion production
2 nM PD184352 inhibits the activation of MKK1 in Swiss 3T3 cells by 50%
Molecular Weight: 2781
A single dose of Irinotecan significantly increases amounts of topoisomerase I covalently bound to DNA in stomach
ACT-132577 Size:Solid 10 mg RG7834 is a novel oralAprocitentan, also known as ACT 132577, is an endothelin receptor antagonist and an pharmacologically active metabolite of macitentan. Aprocitentan antagonized the specific binding of ET 1 on membranes of cells overexpressing ET(A) and ET(B) receptors and blunted ET 1 induced calcium mobilization in various natural cell lines, with inhibitory constants within the nanomolar range. Product information CAS Number: 1103522 45 7 Molecular Weight: 546. 19
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