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13]tetraazacyclohexadecin-10-yl)-4
PubMed PMID: 16178722
Forodesine hydrochloride is a transition-state analog inhibitor of purine nucleoside phosphorylase
Smiles: C=CC1=CC(O)=CC2N=C(OC=21)C1=CC(F)=C(O)C=C1
AZD1152-HQPA - CAS# 722544-51-6 in 2 (S) 13]tetraazacyclohexadecin-10-yl)-4AZD 1152 HQPA, also known as AZD 2811, is a potent and selective Aurora B inhibitor (IC50 of 0. 37 nM versus 1368 nM for Aurora B and A kinases, respectively), serine threonine kinase inhibitor, and an active metabolite of Barasertib ( AZD 1152). Barasertib is a prodrug and will be converted rapidly to the active drug AZD1152 HQPA in human plasma. Preliminary studies showed that AZD 1152 was active against a variety of solid tumors including colon,
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