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ELA-11(human) TFA Catalog No.:M17698-C A single administration of FRAX486

SKU: 90435540503

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Description

A single administration of FRAX486 is sufficient to rescue all of these phenotypes in adult Fmr1 KO mice

InChiKey: PUYVJBBSBPUKBT-UHFFFAOYSA-N

DC10SMe is a active cyclopropyl form

InChi: InChI=1S/C174H278N52O51S6/c1-13-87(9)135(138(185)243)223-149(254)106(51-54-128(182)234)201-152(257)110(68-92-45-47-94(232)48-46-92)206-144(249)100(39-22-27-59-177)198-162(267)122-80-280-282-82-124-167(272)220-123-81-281-279-79-121(217-140(245)96(180)49-55-131(237)238)164(269)205-108(65-84(3)4)151(256)202-107(52-56-132(239)240)150(255)224-136(88(10)14-2)170(275)210-111(67-91-33-16-15-17-34-91)153(258)195-98(37-20-25-57-175)141(246)193-89(11)139(244)216-120(165(270)211-115(71-130(184)236)172(277)226-64-32-44-126(226)168(273)215-119(77-230)160(265)208-113(70-129(183)235)155(260)209-114(72-133(241)242)156(261)200-105(147(252)218-124)50-53-127(181)233)78-278-283-83-125(221-169(274)134(86(7)8)222-157(262)109(66-85(5)6)204-143(248)99(38-21-26-58-176)196-158(263)116(74-227)213-161(266)118(76-229)212-146(251)101(199-163(123)268)40-23-28-60-178)166(271)214-117(75-228)159(264)197-103(42-30-62-190-173(186)187)142(247)194-102(41-24-29-61-179)148(253)225-137(90(12)231)171(276)203-104(43-31-63-191-174(188)189)145(250)207-112(154(259)219-122)69-93-73-192-97-36-19-18-35-95(93)97/h15-19

ELA-11(human) TFA Catalog No.:M17698-C A single administration of FRAX486ELA 11(human) TFA is a high affinity apelin receptor agonist (Ki=14 nM). ELA 11(human) TFA is a bioactive fragment of ELA 32. ELA 11(human) TFA inhibits forskolin induced cAMP production and stimulates arrestin recruitment in vitro. Product information Molecular Weight: 1397. 59 Formula: C60H91F3N16O15S2 Chemical Name: (2 (2 (2 (2 (1 (cysteinylmethionyl)pyrrolidine 2 carboxamido) 4 methylpentanamido) 3 (1H imidazol 5 yl)propanamido) 3

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