PF-562271 hydrochloride Size:Contact [email protected] for quotation Smiles: CC1N=CSC=1C1C=CC(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCN)C(C)(C)C)=CC=1

Smiles: CC1N=CSC=1C1C=CC(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCN)C(C)(C)C)=CC=1

The p53R175H-dependent effects are strong over a broad range of concentrations

2017 Jun 2

It was approved by the US FDA in October 2012 for the treatment of adult patients with CML with resistance and/or intolerance to two or more tyrosine kinase inhibitors (TKIs)

PF-562271 hydrochloride Size:Contact [email protected] for quotation Smiles: CC1N=CSC=1C1C=CC(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCN)C(C)(C)C)=CC=1PF 562271 hydrochloride is a potent, ATP competitive and reversible FAK and Pyk2 kinase inhibitor with IC50s of 1. 5 nM and 13 nM, respectively. Product information CAS Number: 939791 41 0 Molecular Weight: 543. 95 Formula: C21H21ClF3N7O3S Chemical Name: N methyl N {3 [({2 [(2 oxo 2,3 dihydro 1H indol 5 yl)amino] 5 (trifluoromethyl)pyrimidin 4 yl}amino)methyl]pyridin 2 yl}methanesulfonamide hydrochloride Smiles: Cl.