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iRucaparib-AP6 (0-10 μM
Mice are treated with UNC4203 (compound 24) at a dose of 10 mg/kg administered via oral (po) or iv routes
treatment with 30 mg/kg RB394 in drinking water for two weeks resulted in a final plasma concentration of ~3 μM
TAS-116 (12
CM-675 Catalog No.:M24149-C iRucaparib-AP6 (0-10 μMCM 675 is a dual phosphodiesterase 5 (PDE5) and class I histone deacetylases selective inhibitor, with IC50 values of 114 nM and 673 nM for PDE5 and HDAC1, respectively. CM 675 has potential to treat Alzheimers disease. Product information CAS Number: 1872466 47 1 Molecular Weight: 536. 62 Formula: C31H32N6O3 Chemical Name: N (2 aminophenyl) 4 [(4 ethoxy 3 {1 methyl 7 oxo 3 propyl 1H,6H,7H pyrazolo[4,3 d]pyrimidin 5 yl}phenyl)methyl]benzamide Smiles:
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