Netarsudil Mesylate - CAS# 1422144-42-0 Catalog No.:M6862-10 with an IC50 of 3

Name: Netarsudil Mesylate - CAS# 1422144-42-0 Catalog No.:M6862-10 with an IC50 of 3
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Description

with an IC50 of 3

Pietranico-Cole S

Dembinski JL

Methods Enzymol

Netarsudil Mesylate - CAS# 1422144-42-0 Catalog No.:M6862-10 with an IC50 of 3Netarsudil Mesylate, CAS No. 1422144 42 0, also known as AR 11324, is a Rho associated protein kinase inhibitor. Netarsudil is potential useful for treating glaucoma and or reducing intraocular pressure. Netarsudil Increases Outflow Facility in Human Eyes Through Multiple Mechanisms. Netarsudil inhibited kinases ROCK1 and ROCK2 with a Ki of 1 nM each, disrupted actin stress fibers and focal adhesions in TM cells with IC50s of 79 and 16 nM,

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