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HLI 373 dihydrochloride Catalog No.:M8040-10 GSK343 significantly inhibited the invasion

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Description

GSK343 significantly inhibited the invasion of EOC cells

Am J Transl Res

Chelsea E Powell

1080/15384101

HLI 373 dihydrochloride Catalog No.:M8040-10 GSK343 significantly inhibited the invasionHLI 373 is an inhibitor of Hdm2 ubiquitin ligase (E3) that blocks Hdm2 mediated ubiquitylation and proteasomal degradation of p53. HLI 373 induces apoptosis in several tumor cell lines that express wild type p53 such as LOX IMVI, A549, HT1080 and U2OS. Product information CAS Number: 1782531 99 0 Molecular Weight: 414. 33 Formula: C18H25Cl2N5O2 Chemical Name: 5 ((3 (dimethylamino)propyl)amino) 3, 10 dimethylpyrimido[4, 5 b]quinoline 2, 4(3H, 10H)

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