BAN ORL 24 dihydrochloride Size:Contact [email protected] for quotation Smiles: [2H]C([C@]([2H])(NC(=O)[C@@H](NC)C(C)C)C(=O)N(C)[C@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](CC1C=CC=CC=1)C1=NC=CS1)OC)[C@@H](C)CC)(C([2H])([2H])[2H])C([2H])([2H])[2H]

Smiles: [2H]C([C@]([2H])(NC(=O)[C@@H](NC)C(C)C)C(=O)N(C)[C@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](CC1C=CC=CC=1)C1=NC=CS1)OC)[C@@H](C)CC)(C([2H])([2H])[2H])C([2H])([2H])[2H]

6-Biphosphatase 3) with IC50 of 0

blocks Wnt-induced LRP6 phosphorylation

25)23-7-10-6-22(8-16(10)21-23)12-5-15(20)17(26-9-12)13-4-11(18)2-3-14(13)19/h2-4

BAN ORL 24 dihydrochloride Size:Contact [email protected] for quotation Smiles: [2H]C([C@]([2H])(NC(=O)[C@@H](NC)C(C)C)C(=O)N(C)[C@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](CC1C=CC=CC=1)C1=NC=CS1)OC)[C@@H](C)CC)(C([2H])([2H])[2H])C([2H])([2H])[2H]BAN ORL 24 is a potent and selective NOP receptor antagonist. (IC50 values are 0. 27, 2500, 6700 and > 10000 nM for NOP, , and receptors respectively). IC50 value: 0. 27 nM Target: NOP receptor BAN ORL 24 inhibits nociceptin induced stimulation of [35S] GTPS binding and Ca2+ mobilization in CHO cells in vitro. BAN ORL 24 antagonizes NOP agonist induced reduction in locomotor activity in vivo. Brain penetrant. Product information CAS Number: 1401463 54