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It has a dual function in estrogen activation and androgen inactivation and plays a major role in establishing the estrogen E2 concentration gradient between serum and peripheral tissues
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such as mitogenic activation
Swissprot No Q9UNA0 Gene Accession NP_008969 WB Predicted band size 102 kDa WB Positive control WB Recommended dilution 500-2000 IHC predicted cell location Predicted cell location: Cytoplasm IHC positive control Positive control: Human liver cancer IHC Recommed dilution Recommended dilution: 50-100 Storage
Recombinant Human Noggin Protein PCR Master Mixes It has a dual functionDescription Noggin is a secreted dimeric glycoprotein that is widely expressed in vertebrates and is highly conserved among different vertebrate species. Noggin is a key regulator that modulates the formation of ectoderm , mesoderm , and endoderm derived tissues and plays a critical role in bone development, joint formation, and neural tube closure. Noggin regulates the BMP signaling pathway by binding to BMPs and preventing them from interacting with
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