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GSK-2981278 markedly and potently inhibits IL-17A and IL-22 protein secretion in a concentration dependent manner (IC50 = 3
1021/jm100812a
InChi: InChI=1S/C26H22N2O2/c1-18(19-9-3-2-4-10-19)28-26(30)22-13-7-8-14-24(22)27-17-23-21-12-6-5-11-20(21)15-16-25(23)29/h2-18
CAS Number: 127254-12-0
Vancomycin 60312 GSK-2981278 markedly and potently inhibitsVancomycin is an antibiotic used to treat a number of bacterial infections. Vancomycin acts by inhibiting proper cell wall synthesis in gram positive bacteria. Due to the different mechanism by which gram negative bacteria produce their cell walls and the various factors related to entering the outer membrane of gram negative organisms, vancomycin is not active against gram negative bacteria (except some nongonococcal species of Neisseria). The large
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