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Apremilast D5 18274 InChi: InChI=1S/C22H24ClN3O/c1-25-13-4-5-18(12-14-25)26-22(27)20-7-3-2-6-19(20)21(24-26)15-16-8-10-17(23)11-9-16/h2-3

SKU: 37418412993

4.8
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Description

InChi: InChI=1S/C22H24ClN3O/c1-25-13-4-5-18(12-14-25)26-22(27)20-7-3-2-6-19(20)21(24-26)15-16-8-10-17(23)11-9-16/h2-3

pp 850–855

CAS Number: 898235-65-9

Jayakody L

Apremilast D5 18274 InChi: InChI=1S/C22H24ClN3O/c1-25-13-4-5-18(12-14-25)26-22(27)20-7-3-2-6-19(20)21(24-26)15-16-8-10-17(23)11-9-16/h2-3Apremilast D5 (CC 10004 D5) is a deuterium labeled Apremilast. Apremilast is an orally available inhibitor of type 4 cyclic nucleotide phosphodiesterase (PDE 4) with an IC50 of 74 nM. Apremilast inhibits TNF release by lipopolysaccharide (LPS) with an IC50 of 104 nM. Product information CAS Number: 1258597 47 5 Molecular Weight: 465. 53 Formula: C22H24N2O7S Chemical Name: N {2 [(1S) 1 {3 [(1,1,2,2,2 H)ethoxy] 4 methoxyphenyl} 2 methanesulfonylethyl]

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