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m-PEG4-CH2-methyl ester is a PEG- and Alkyl/ester-based PROTAC linker can be used in the synthesis of PROTACs
Since mice spend more time exploring unfamiliar objects
InChi: InChI=1S/C21H22O6/c1-11(2)5-8-17(27-18(25)9-12(3)4)13-10-16(24)19-14(22)6-7-15(23)20(19)21(13)26/h5-7
InChiKey: KTAQQSUPNZAWEY-OSPHWJPCSA-N
Nav1.7-IN-8 opressin(rat) m-PEG4-CH2-methyl ester is a PEG-Nav1. 7 IN 8 is a potent blockage of NaV1. 7 with high selectivity for the inhibition of NaV1. 7 over the subtypes hNaV1. 1 and hNaV1. 5. Nav1. 7 IN 8 inhibits CYP2C9 and CYP3A4 with an IC50 of 0. 17 M and 0. 077 M, respectively. Nav1. 7 IN 8 displays significant analgesic effects in rodent models of acute and inflammatory pain. Product information CAS Number: 1432913 44 4 Molecular Weight: 535. 93 Formula: C21H12ClF2N5O4S2 Chemical Name: 4 [2 (3
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