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Johnson ME
Epub 2014 Jun 25
CAS Number: 2070015-10-8
As a precursor of photoactive porphorins
L-2-Hydroxyglutaric acid disodium 0302 Johnson MEL 2 Hydroxyglutaric acid disodium ((S) 2 Hydroxyglutaric acid disodium, L 2 Hydroxyglutarate disodium, LGA, L 2HG) is an epigenetic modifier and a putative oncometabolite in kidney cancer that inhibits histone demethylases and hence promotes histone methylation. L 2 Hydroxyglutaric acid disodium is also an inhibitor of mitochondrial creatine kinase (Mi CK) with Km and Ki of 2. 52 mM and 11. 13 mM, respectively. Product information CAS Number: 63512 50